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Genetic prevention of postnatal TCS craniofacial anomalies. Shown are frontal and lateral views highlighting restoration of normal craniofacial morphology through loss of p53 function. (a,b) Tcof1+/+Trp53+/− mouse. (c,d) Tcof1+/+Trp53−/− mouse. (e,f) Tcof1+/−Trp53+/− mouse. (g,h) Tcof1+/−Trp53−/− mouse. All mice were on a mixed DBA × C57BL/6 background.
