Table 2.

Aminosalicylate Drug Interactions

Drug	Drug-Drug Interaction	Cytochrome Association	Renal Impairment	Hepatic Impairment
Aminosalicylates	5-ASA derivatives: may decrease the metabolism of thiopurine analogs (azathioprine, mercaptopurine, thioguanine) 5-ASA derivatives: may decrease the absorption of cardiac glycosides (digitoxin, digoxin)	None	Use with caution— minimal change nephropathy and acute/chronic interstitial nephritis have been reported	Use with caution

5-ASA=5-aminosalicylic acid.