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. Author manuscript; available in PMC: 2012 Apr 29.
Published in final edited form as: J Mol Biol. 2011 Feb 24;408(2):252–261. doi: 10.1016/j.jmb.2011.02.042

Figure 3.

Figure 3

Comparison between T-T dimer and undamaged DNA ternary Polκ complexes. (A) Superimposition of the T-T dimer complex (red) and the complex with undamaged DNA (blue; PDB code 2OH2) (blue). Highlighted are the template bases (T-T dimer and A), incoming dNTPs (dATP and dTTP) and residues within the active site cleft. The putative Mg2+ ion is shown as a sphere in each structure. (B) Close-up views of the superposition of the T-T dimer (magenta) and undamaged DNA (blue), and the incoming nucleotides dATP (magenta) and dTTP (blue), respectively. The figure also shows the catalytic triad and the putative Mg2+ ion in each structure. The figure shows that the active site geometry is conserved in the damaged and undamaged structures.