Fig. 1.

Angiotensin-converting enzyme 2 (ACE2) expression in the mouse brain. ACE2 is widely expressed throughout the mouse brain, including in key brain regions involved in the regulation of blood pressure and body fluid homeostasis. This shows examples of ACE2 expression (red) in the subfornical organ (SFO), the neurons of the paraventricular nucleus (PVN), the nucleus of tractus solitarii (NTS), the dorsal motor nucleus of the vagus (DMNX), and the rostral ventrolateral medulla (RVLM). Green: MAP2 (neuronal marker); blue: DAPI (nuclei marker). CVLM—caudal ventrolateral medulla; IML—intermediolateral cell column; NA—nucleus ambiguus