Locomotor activity, energy expenditure, and food consumption of MGL-ko mice are unchanged. Mice were housed in a laboratory animal monitoring system (LabMaster, TSE Systems), which allows the simultaneous measurement of locomotor activity (a), O2 consumption (VO2) (b), CO2 production (VCO2) (c), and food consumption (d). Mean values were calculated from a 72-h monitoring period of mice that have been familiarized with metabolic cages for at least 3 days (n = 5 for each genotype). Data are presented as mean ± S.D.