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Superposition of C8α (red) on C8β (blue) based on their upper MACPF subdomains. MACPF domains are in dark colors, and modules are in light colors. This superposition yields a 24° angle between strands of the β-sheets in the lower subdomain. The region with conserved glycine pairs 318–319, 395–396 and 297–298, 375–376 (numbering for C8α and C8β, respectively) is located at the bends of the sheets (circled). Two orthogonal views are shown.
