C12R1, unlike anionic uncouplers, affects yeast cells, depending on their mitochondrial membrane potential. Shown are the dependences of stimulation of yeast cell respiration rate (V/V0) and growth on the concentration of FCCP (A) and C12R1 (B). C, C12R1 (10 μm; dark gray) or DNP (500 μm; light gray) were added to yeast cells (grande or petite) growing on non-fermentable (glycerol) or fermentable (glucose) carbon sources. The growth rate without uncouplers corresponds to 100%. Error bars, S.E.