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Temporal and spatial segregation of plasmalemmal translocations of annexins A1 and A6. A and B, HEK 293 cells double-transfected with annexin A6 (AnxA6)-CFP and annexin A1 (AnxA1)-YFP were treated with SLO (100 ng/ml) at time point = 0. The intracellular dynamics of two annexins were analyzed by confocal microscopy. Two individual cells are shown. Arrows denote plasmalemmal puncta of annexin A1 within the cell body. Scale bar, 10 μm.
