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. 2011 Mar 17;286(20):18093–18103. doi: 10.1074/jbc.M111.221184

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© 2011 by The American Society for Biochemistry and Molecular Biology, Inc.

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FIGURE 6. — The new interactors of PTEN are involved in the migration and apoptosis signaling pathways. Network maps of cell migration (A) and apoptosis (B) for PTEN interactors from SILAC-based PAP-SILAC were created by using information gathered from published literature and MetaCore^TM (version 6.0). The double-headed arrow indicates interaction of proteins. Facilitation is a green arrow (single-headed arrow), and inhibition is a red line. The known partner proteins of PTEN are implicated in the control of migration and apoptosis. Com, common interactors; WTsp, wild type specific interactors; G20Esp, G20E mutant interactors; PML, promyelocytic leukemia protein.