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Inhibition of ROCK regulates HAS expression. mRNA expression in human fibroblasts was determined by real time RT-PCR. A, mRNA expression after incubation with latrunculin A (3 μmol/liter, 24 h) or the ROCK inhibitor Y27632 (10 μmol/liter, 24 h). B, the ROCK activator lysophosphatidic acid (LPA, 300 nmol/liter) plus or minus CF was added for 24 h; n = 3–5, mean ± S.E., *, p < 0.05.
