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Changes in body weight (A) and fat-pad weight (B) in brain-specific suppressor of cytokine signaling-3 (SOCS3)-deficient (Socs3-fl/fl-Cre) and wild-type (Socs3-fl/fl) mice. E-fat, epididymal fat; RP-fat, retroperitoneal fat; BAT, brown adipose tissue. Values are expressed as the means ± SE for the number of animals indicated in parentheses. *P < 0.01 vs. Socs3-fl/fl-Cre group, and aP < 0.05 vs. Socs3-fl/fl group.
