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Effect of 2ME2 treatment on 2K/TBW, cyst volume density, and BUN in Cy/+ rats
| +/+ Vehicle | +/+ 2ME2 | Cy/+ Vehicle | Cy/+ 2ME2 | |
|---|---|---|---|---|
| 2K/TBW, % | 0.8 | 0.8 | 1.8* | 2* |
| CVD | 1 | 2 | 30.3* | 27.4* |
| BUN | 21 | 18 | 30* | 28* |
2M2, 2-methoxyestradiol; CVD, cyst volume density; BUN, blood urea nitrogen.
2ME2 treatment had no effect on 2K/TBW, CVD, and BUN in Cy/+ rats (n = 4-5/group).
P < 0.05 vs. +/+ vehicle.
