Fig. 1.

Vitronectin (Vtn) expression is increased in unilateral ureteral obstruction (UUO) nephropathy. A: Vtn Western blot illustrates increased kidney protein expression in wild-type (Vtn+/+) mice 7, 14, and 21 days after UUO compared with sham kidneys. B: graph shows Vtn band densities (means ± SD) corrected for protein loading using β-actin densities. Kidney Vtn mRNA levels measured by real-time RT-PCR (means ± 1 SD, 5 samples/time point) confirmed significantly increased levels after UUO compared with the sham kidney levels.