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A: representative calcium traces with carbenoxolone (CBX) and without (control) upon termination of rapid pacing (215 beats/min). CBX does not suppress m-SCR activity but, surprisingly, increases m-SCR amplitude and decreases m-SCR Tp. Similar results were observed over all experiments (B and C). CBX also decreases the Tp range (D) similar to the effect of CAFF (Fig. 6B).
