Table 1.

Gene expression profiles in aortas from 6T/ApoE^−/− mice compared with ApoE^−/− mice

			NC		WD
Gene Name	Gene Abbreviation	GenBank Accession Number	Relative Expression	P value	Relative Expression	P value
Chemokine (C-C motif) receptor 1	Ccr1	NM_009912	2.16	0.04	−1.07	0.52
Chemokine (C-C motif) receptor 2	Ccr2	NM_009915	1.99	0.08	−1.65	0.38
Chemokine (C-C motif) ligand 2	Ccl2	NM_011333	2.85	0.20	1.13	0.66
Platelet-derived growth factor B polypeptide	Pdgfb	NM_011057	1.71	0.11	1.49	0.29
Connective tissue growth factor	Ctgf	NM_010217	−2.04	0.09	−1.58	0.16
ATP-binding cassette, subfamily A, member 1	Abca1	NM_013454	1.83	0.23	2.14	0.01
Angiotensin I-converting enzyme 1	Ace	NM_009598	1.22	0.87	2.22	0.01
Fibrinogen, α-chain	Fga	NM_010196	−2.01	0.91	2.38	0.19
Fibrinogen, β-chain	Fgb	NM_181849	−2.01	0.91	2.83	0.18
Interleukin-4	Il4	NM_021283	−2.01	0.91	2.38	0.19
Interleukin-5	Il5	NM_010558	−1.68	0.94	2.22	0.19
Integrin, α5	Itga5	NM_010577	−1.08	0.53	1.57	0.15
Kruppel-like factor-2	Klf2	NM_008452	−2.01	0.91	2.38	0.19
Laminin, α1	Lama1	NM_008480	−2.01	0.91	2.64	0.15
Lipoprotein lipase	Lpl	NM_008509	−1.14	0.72	1.83	0.09
Matrix metallopeptidase-1a	Mmp1a	NM_032006	−2.01	0.91	2.22	0.20
Macrophage scavenger receptor-1	Msr1	NM_031195	1.51	0.57	2.69	0.04
Nuclear receptor, subfamily 1, group H, member 3	Nr1 h3	NM_013839	−1.33	0.87	1.65	0.11
Serine (or cysteine) peptidase inhibitor, member 1	Serpine1	NM_008871	1.31	0.51	1.77	0.0495
Secreted phosphoprotein-1	Spp1	NM_009263	1.44	0.43	4.76	0.01
Tenascin C	Tnc	NM_011607	1.26	0.69	1.80	0.14
B cell leukemia/lymphoma 2	BclII	NM_009741	−1.14	0.55	−1.74	0.11
Heparin-binding EGF-like growth factor	Hbegf	NM_010415	−1.55	0.25	−2.18	0.16
Lysophospholipase-1	Lypla1	NM_008866	1.24	0.57	−2.14	0.13
Collagen, type III, α1	Col3a1	NM_009930	1.13	0.64	1.60	0.29
Peroxisome proliferator activated receptor-γ	Pparg	NM_011146	1.06	0.65	−4.14	0.50
Tumor necrosis factor-α	Tnf	NM_013693	−2.01	0.91	1.34	0.72

ApoE, apolipoprotein E; ApoE^−/− mice, ApoE-deficient mice; 6T/ApoE^−/− mice, ApoE^−/− mice with 6T alleles; NC, normal chow; WD, Western diet.