Table 3.

Gene expression profiles in IGF-I-treated THP-1 macrophages

			Relative Expression
Gene Name	Abbreviation	GenBank Accession Number	IGF-I vs. control	P value
Bcl2-associated X protein	BAX	NM_007527	0.5791	0.031558
Chemokine (C-C motif) ligand 2	Ccl2	NM_011333	0.5219	0.071173
Chemokine (C-C motif) receptor 1	Ccr1	NM_009912	1.0082	0.92297
Chemokine (C-C motif) receptor 2	Ccr2	NM_009915	2.0876	0.376459
CD44 molecule (Indian blood group)	CD44	NM_000610	0.4869	0.20049
Colony-stimulating factor 1 (macrophage)	CSF1	NM_000757	0.2012	0.098647
Fibronectin 1	FN1	NM_010233	0.1663	0.114014
Heparin-binding EGF-like growth factor	HBEGF	NM_001945	0.3565	0.058545
Intercellular adhesion molecule 1	ICAM1	NM_000201	0.2233	0.034123
Interferon (α, β, and ω) receptor 2	IFNAR2	NM_000874	0.7007	0.102391
Interleukin 1 receptor, type I	IL1R1	NM_000877	0.3157	0.055
Interleukin 1 receptor, type II	IL1R2	NM_010555	0.2846	0.206441
Integrin, α5 (fibronectin receptor-α)	ITGA5	NM_010577	0.2797	0.014981
Integrin, β2	ITGB2	NM_008404	0.4313	0.152814
Matrix metallopeptidase-1 (interstitial collagenase)	MMP1	NM_002421	0.1579	0.01098
Matrix metallopeptidase-3 (stromelysin-1, progelatinase)	MMP3	NM_002422	0.1978	0.160551
Macrophage scavenger receptor-1	MSR1	NM_031195	0.191	0.067798
Nuclear factor of κ-light polypeptide gene enhancer in B cells-1	NFKB1	NM_003998	0.4313	0.1815
Platelet-derived growth factor B polypeptide	PDGFB	NM_011057	0.369	0.159103
Prostaglandin-endoperoxide synthase-1 (prostaglandin G/H synthase and cyclooxygenase)	PTGS1	NM_000962	0.4313	0.223673
Serine (or cysteine) peptidase inhibitor, member 1	SERPINE1	NM_008871	0.5892	0.207759
Secreted phosphoprotein-1	SPP1	NM_009263	0.3213	0.067696
Transforming growth factor, β1	TGFB1	NM_000660	0.5041	0.195858
Transforming growth factor, β2	TGFB2	NM_003238	0.4389	0.0537
Tumor necrosis factor-α	TNF	NM_013693	0.5403	0.20983