Table 1. Activities of CaMKII variants.

Protein	Activity (μmol/min/μg)
Mouse CaMKIIα holoenzyme WT	5.62±0.15
Mouse CaMKIIα 1–380 WT	7.13±0.16
C. elegans 1–340 WT	6.04±0.76
C. elegans 1–340 WT*	4.59±0.05
C. elegans 1–340 D135N*	0*
Average and range of activities of CaMKII variants determined by incorporation of radiolabelled phosphate from [γ32P]ATP onto the peptide substrate syntide-2 (n=2). *P<0.01 versus ‘mouse CaMKIIα holoenzyme WT’ and ‘C. elegans 1–340 WT*’ by ANOVA followed by Bonferroni post-test: activities of all other kinases are not statistically different from WT mouse CaMKIIα holoenzyme.