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. 2010 Dec 23;300(5):G853–G861. doi: 10.1152/ajpgi.00459.2010

Fig. 4.

Fig. 4.

HIF-1 plays a role in gut I/R-induced lung injury. WT and HIF-1α+/− mice were subjected to SMAO or sham for 45 min and 3 h of reperfusion. A: MPO activity (U/mg of protein) was measured in the lung homogenates. Values expressed as means ± SE (n = 5–8/group). B: real-time PCR analysis of cytokines in the lung was performed using the ΔΔCt method. IL-6 and IL-10 expression was normalized to 18S, and the relative expression was compared with WT sham controls. Values are expressed as means ± SE (n = 4–6 mice/group).