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. 2010 Dec 23;300(5):G853–G861. doi: 10.1152/ajpgi.00459.2010

Fig. 5.

Fig. 5.

Duration of the intestinal ischemic insult dictates the functional sequelae of the intestinal HIF-1 response. WT and HIF-1α+/− mice were subjected to SMAO or sham for 15 min and 3 h of reperfusion. A: HIF-1α protein levels (pg/ml) in the ileal mucosa were quantified in a HIF-1α ELISA. Values are expressed as means ± SE (n = 8–11 mice/group). B: representative sections of H&E staining of the distal ileum (n = 8–16 mice/group). C: MDA levels (μM/100 μg protein) were measured in whole ileal homogenates. Values are expressed as means ± SE (n = 6 mice/group). D: MPO activity (U/mg of protein) was measured in the lung homogenates (n = 4–8 mice/group).