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Insulin sensitivity assessed from a mixed-meal tolerance test delivered to the stomach (■) or jejunum (□). Whole-body insulin sensitivity was estimated by calculating the composite (Matsuda) insulin sensitivity index (ISI). Data are means of 9 subjects ± SE. There is an effect of time after gastric bypass on insulin sensitivity (P = 0.001), but no effect of route (P = 0.902) or route × time interaction (P = 0.819).
