Table 2.
Analysis of dopamine and metabolites in mesencephalic dopaminergic systems of CBL-rGFRα1 mice
Genotype | n | Ventral mesencephalon
|
Striatum
|
|||||
---|---|---|---|---|---|---|---|---|
DA | HVA | DOPAC | DA | HVA | DOPAC | HVA/DA | ||
WT | 6 | 6.5 ± 0.3 | 3.9 ± 0.4 | 2.3 ± 0.1 | 105.8 ± 7.4 | 13.3 ± 1.2 | 7.6 ± 0.7 | 0.12 ± 0.01 |
MT | 6 | 7.3 ± 1.5 | 3.9 ± 0.2 | 2.2 ± 0.2 | 96.2 ± 7.9 | 10.1 ± 1.3 | 7.3 ± 0.3 | 0.10 ± 0.01 |
DT | 6 | 6.2 ± 0.6 | 3.6 ± 0.4 | 2.5 ± 0.2 | 93.3 ± 10.8 | 11.3 ± 1.4 | 7.4 ± 0.9 | 0.12 ± 0.01 |
DA, dopamine; DOPAC, dihydroxyphenylacetic acid; DT, double transgenic; HVA, homovanillic acid; MT, monotransgenic; WT, wildtype.