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. 2011 Feb 23;105(5):2108–2120. doi: 10.1152/jn.01037.2010

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Fig. 6. — Effects of group I mGluR activation on synaptic input to motoneurons. A: Rhythmic locomotor-related drive currents recorded from a motoneuron held at −60 mV in control conditions, in the presence of DHPG (10 μM), and after drug washout. B: amplitude of locomotor-related drive was significantly decreased by DHPG (10 μM) application (n = 10). C: miniature excitatory postsynaptic currents (mEPSCs) recorded from a motoneuron in the presence of tetrodotoxin (TTX; 0.5 μM), bicuculline (10 μM), and strychnine (5 μM). D: cumulative probability plots showing a significant decrease in mEPSC amplitude (i) and frequency (ii) following DHPG (50 μM) application. E: pooled data demonstrating that DHPG caused a significant decrease in both mEPSC amplitude (i) and frequency (ii) (n = 13). *Significantly different from control.