Table 4.

Effects of calcium channel blockers on properties of RB and DL neurons

	RB			DL
	Control	Amiloride	Nimodipine	Control	Amiloride	Nimodipine
n	36	8	8	28	8	5
Number of APs	1.0	1.0	1.0	6.5	8	3
Rheobase current, pA	229.3	427.1†	220.9	112.9	126.6	107.6
AP threshold, mV	−20.8	−26.8	−29.7	−25.4	−26.6	−25.5
AP peak, mV	44.8	32.9*	33.5*	45.9	−4.5†	8.9†
AP duration, ms	1.2	1.1	1.1	0.87	0.57†	0.55†
Maximum rate of depolarizatin, mV/ms	140.8	154.6	152.8	156.5	101.3†	99.7†
Maximum rate of repolarization, mV/ms	53.1	59.9	56.8	80.1	85.4	84.6
AHP peak, mV	−47.6	−62.9*	−56.1	−50.3	−43.2	−38.3

Mean values in control conditions and in the presence of drugs are compared for each parameter, with the exception of AP number, where the median value is reported.

^*P value between 0.0001 and 0.05;

^†P value <0.0001.