Table 5.
Effects of muscarine on properties of RB and DL neurons
| RB |
DL |
|||
|---|---|---|---|---|
| Control | Muscarine | Control | Muscarine | |
| n | 36 | 11 | 28 | 7 |
| Number of APs | 1.0 | 1.0 | 6.5 | 3.0* |
| Rheobase current, pA | 229.3 | 246.5 | 112.9 | 61.5† |
| AP threshold, mV | −20.8 | −28.9 | −25.5 | −27.2 |
| AP peak, mV | 44.8 | 37.5 | 45.9 | 44.2 |
| AP duration, ms | 1.2 | 1.0* | 0.87 | 0.77 |
| Maximum rate of depolarizatin, mV/ms | 140.8 | 162.1 | 156.5 | 143.0 |
| Maximum rate of repolarization, mV/ms | 53.1 | 57.4 | 80.1 | 72.8 |
| AHP peak, mV | −47.6 | −49.6 | −50.3 | −30.8 |
Mean values in control conditions and in the presence of drugs are compared for each parameter, with the exception of AP number, where the median value is reported.
P value between 0.0001 and 0.05;
P value <0.0001.