Table 2.
Sequence alignment of amino acid residues of the S1 glycoprotein of IBV strains with the M41 strain
| Strains | Deletions1 | Insertions2 | Cleavage recognition motifs |
|---|---|---|---|
| CQ8 | 119(2)GL, 140(2)NS | RRTGRa | |
| CQ9 | 21(1)D, 118(1)G | 72(7)YTNGNDV | HRRRRb |
| MS1 | 21(1)D, 118(1)G | 72(7)YTNGNDV | HRRRRb |
| PT1 | 21(1)D, 118(1)G | 72(7)YTNGNDV | RRSRRc |
| PT2 | 117(2)GV, 286(1)N | RRLRRd | |
| PT3 | 21(1)D, 118(1)G | 72(7)YTNGNDV | RRSRRc |
| PT4 | 21(1)D, 118(1)G | 72(7)YTNGNDV | RRSRRc |
| BT | 119(2)GS | RRFRRe | |
| Y4 | 117(2)GI, 286(1)N | RRFRRe | |
| Y9 | 117(2)GI, 286(1)N | RRFRRe | |
| FML | 21(1)D, 118(1)G | 72(7)YTNGNDV | RRFRRe |
| HY | 117(2)GV, 286(1)N | RRLRRd | |
| HY41 | 21(1)D, 118(1)G | 72(7)YTNGNDV | RRFRRe |
| HY42 | 21(1)D, 118(1)G | 72(7)YTNGNDV | RRFRRe |
| HY51 | 23(1)S, 118(1)G | 72(7)YTNGNDV, 286(1)G | RRFRRe |
| HY52 | 23(1)S, 118(1)G | 72(7)YSNGNDV | RRSKRf |
| HY1 | 21(1)D, 118(1)G | 72(7)YTNGNDV | RRFRRe |
| HY2 | 23(1)S, 118(1)G | 72(7)YSNGNDV | RRSKRf |
| HY3 | 21(1)D, 118(1)G | 72(7)YTNGNDV | RRFRRe |
| KY | 24(1)N, 119(2)GS | HRRRRb | |
| LZ1 | 24(1)N, 119(2)GS | HRRRRb | |
| LZ2 | 24(1)N, 119(2)GS | HRRRRb | |
| LZ3 | 24(1)N, 119(2)GS | HRRRRb | |
| LH | 21(1)D, 118(1)G | 72(7)YTNGNDV | RRFRRe |
| SL | 24(1)N, 119(2)GS | HRRRRb | |
| ST1 | 119(2)GS | RRFRRe | |
| ST3 | 119(2)GS | RRFRRe | |
| WL | 21(1)D, 118(1)G | 72(7)YTNGNDV | HRRRRb |
| XD2 | 119(2)GS | RRFRRe | |
| XD3 | 24(1)N, 119(2)GS | RRFRRe | |
| XN | 24(1)N, 119(2)GS | RRFRRe | |
| XN1 | 25(1)N, 119(2)GS | HRRRRb | |
| XN2 | 119(2)GS | RRFRRe | |
| GL1 | 21(1)D, 118(1)G | 72(7)YTNGNDV | HRRRRb |
| GL2 | 117(2)GI, 289(1)N | RRLRRd | |
| GL | 25(1)N, 119(2)GS | HRRRRb | |
| HEZ | 21(1)D, 118(1)G | 72(7)YTNGNDV | RRFRRe |
| LC | 118(1)G | 72(7)YTNGNDV, 286(1)S | RRFRRe |
| LC1 | 117(2)GI | RRFRRe | |
| LC2 | 117(2)GI | RRFRRe | |
| LC3 | 117(2)GI | RRFRRe | |
| LC4 | 117(2)GI | RRFRRe | |
| LC5 | 117(2)GI | RRFRRe | |
| LC6 | 21(1)D, 118(1)G | 72(7)YTNGNDV | RRFRRe |
| LC7 | 117(2)GI | RRFRRe | |
| LC8 | 117(2)GI | RRFRRe | |
| LC9 | 21(1)D, 118(1)G | 72(7)YTNGNDV | RRFRRe |
| NN | 117(2)GI, 286(1)N | RRLRRd | |
| YL08 | 117(2)GI, 286(1)N | RRLRRd | |
| YL4 | 24(1)S, 118(1)G | 72(7)YTNGNDV | RRFRRe |
| YL6 | 24(1)N, 119(2)GS | HRRRRb | |
| HN08 | 119(2)GS | RRFRRe | |
| HN1 | 21(1)D, 118(1)G | 72(7)YTNGNDV | RRFRRe |
| HN2 | 21(1)D, 118(1)G | 72(7)YTNGNDV | RRFRRe |
| HN31 | 21(1)D, 118(1)G | 72(7)YTNGNDV | RRFRRe |
| HN32 | 21(1)D, 118(1)G | 72(7)YTNGNDV | RRFRRe |
| HN33 | 21(1)D, 118(1)G | 72(7)YTNGNDV | RRFRRe |
| HN34 | 21(1)D, 118(1)G | 72(7)YTNGNDV | RRFRRe |
| HN41 | 21(1)D, 118(1)G | 72(7)YTNGNDV | RRFRRe |
| HN42 | 21(1)D, 118(1)G | 72(7)YTNGNDV | RRFRRe |
| HN43 | 21(1)D, 118(1)G | 72(7)YTNGNDV | RRFRRe |
| HN44 | 21(1)D, 118(1)G | 72(7)YTNGNDV | RRFRRe |
| WH1 | 24(1)N, 119(2)GS | HRRRRb | |
| WH2 | 24(1)N, 119(2)GS | HRRRRb | |
| WH3 | 25(1)N, 119(2)GS | HRRRRb | |
| WH4 | 25(1)N, 119(2)GS | HRRRRb | |
| LYG | 25(1)N, 119(2)GS | HRRRRb | |
| NJ | RRFRRe | ||
| HZ1 | 25(1)N, 119(2)GS | HRRRRb | |
| HZ2 | 25(1)N, 119(2)GS | HRRRRb | |
| HZ3 | 25(1)N, 119(2)GS | HRRRRb | |
| HZ4 | 21(1)D, 118(1)G | 72(7)YTNGNDV | RRFRRe |
| HZ5 | 25(1)N, 119(2)GS | HRRRRb | |
| HZ6 | 25(1)N, 119(2)GS | HRRRRb | |
| HZ7 | 25(1)N, 119(2)GS | HRRRRb | |
| HZ8 | 25(1)N, 119(2)GS | HRRRRb | |
| HZ9 | 25(1)N, 119(2)GS | HRRRRb | |
| QZ1 | 24(1)N, 119(2)GS | HRRRRb | |
| QZ2 | 24(1)N, 119(2)GS | HRRRRb | |
| QZ3 | 24(1)N, 119(2)GS | HRRRRb |
1 positions of residues in deduced amino acid sequences of the S1 protein of the M41 vaccine strain;
2 positions of residues in deduced amino acid sequences of the S1 protein of the M41 strain between which the residue(s) of other IBVs was (were) inserted.
a, RRTGR: Arg-Arg-Thr-Gly-Arg (1/80); b, HRRRR: His-Arg-Arg-Arg-Arg (28/80); c, RRSRR: Arg-Arg-Ser-Arg-Arg (3/80); d, RRLRR: Arg-Arg-Leu-Arg-Arg 5/80; e, RRFRR: Arg-Arg-Phe-Arg-Arg (41/80); f, RRSKR Arg-Arg-Ser-Lys-Arg (2/80).