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. 2011 May 13;6(5):e19896. doi: 10.1371/journal.pone.0019896

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This is an open-access article distributed under the terms of the Creative Commons Public Domain declaration, which stipulates that, once placed in the public domain, this work may be freely reproduced, distributed, transmitted, modified, built upon, or otherwise used by anyone for any lawful purpose.

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The mean prevalence growth rate is calculated as the average growth rate during the first 10 years of the CWD epidemic. Each point represents the average value for 10 simulations per unique combination of direct and indirect transmission rates, functional forms of transmission, aggregation, and prion persistence. Prion persistence ranges from low (lightest circles = 0.25 year half-life) to high (black circles = 8 year half-life). The empty squares represent values assuming only direct transmission. Plotted data represent only “plausible” simulation results. See Table 1 for β_d and β_i values employed in these simulations.