Figure 1.

2-D cluster analysis of gene expression in ρ^o versus ρ⁺ cells. The first four columns from left to right are replicate hybridizations of cDNAs prepared from early (E; OD₆₀₀ = 0.5) and late (L; OD₆₀₀ = 1.5) log phase cultures of ρ⁺ versus ρ^o cells differentially labeled with Cy3 and Cy5. Data from DeRisi et al. (1997) for the last two time points in the diauxic shift of glucose-grown ρ⁺ cells (OD₆₀₀ = 6.9 and 7.3) are included in the last two columns on the right, indicated as diauxic. All 402 genes showing at least a threefold change in at least two hybridizations are shown. Blue denotes genes induced in ρ^o relative to ρ⁺ or induced during the diauxic shift, and red refers to repressed genes. Mito, mitochondrial; RNP, ribonucleoprotein; UPRT, uracil phosphoribosyl transferase.