Figure 5.

Effects of RTG mutations in ρ^o cells. The four columns on the left are replicate comparisons of early (E) and late (L) log phase ρ⁺ and ρ^o cultures, as detailed in the legend to Figure 1. The six columns on the right are replicate comparisons of ρ^o cells and ρ^o cells containing deletions of rtg1, 2, or 3, respectively, and are based on cultures harvested at an OD₆₀₀ = 0.8. (A–C) Genes whose expression is affected by RTG1, 2, and 3 in ρ^o cells. (D) A group of genes induced by respiratory deficiency in an RTG-independent manner. Blue refers to genes induced in ρ^o relative to ρ⁺ or induced in ρ^o rtg relative to ρ^o RTG. Red refers to repressed genes. All 273 genes that changed by at least threefold in at least two experiments are shown.