Table 1A.
Genes induced in respiratory-deficient cells
| Open reading frame | Gene | Fold change in ρ° | Fold change in antimycin | Oleate induction | Function |
|---|---|---|---|---|---|
| YJL037W | 7.1 | 5.2 | Similar and adjacent to YJL038C | ||
| YDR384C | 5.9 | 4.6 | see YCR010C | Similar to YNR002C and YCR010C | |
| YPR002W | PDH1 | 5.8 | 9.43 | Propionate catabolism | |
| YPR001W | CIT3 | 5.2 | 12.7 | Mitochondrial isoform of citrate synthase | |
| YCR005C | CIT2 | 5.1 | 10.0 | + | Peroxisomal citrate synthase |
| YFL011W | HXT10 | 5.0 | 4.5 | High-affinity hexose transporter | |
| YLR348C | DIC1 | 5.0 | 5.3 | Mitochondrial dicarboxylate transporter | |
| YAL054C | ACS1 | 4.2 | 6.2 | + | Inducible acetyl- and propionyl-CoA synthetase |
| YIL057C | 4.2 | 24.6 | + | ||
| YPL265W | DIP5 | 4.2 | 3.2 | Dicarboxylic amino acid permease | |
| YNL036W | NCE103 | 4.0 | Oxidative damage stress response | ||
| YLR307W | CDA1 | 4.0 | Chitin deacetylase | ||
| YOR374W | ALD4 | 3.7 | + | Aldehyde dehydrogenase | |
| YBR296C | PHO89 | 3.6 | Na+ phosphate symporter | ||
| YOR100C | CRC1 | 3.5 | 5.8 | Mitochondrial carnitine carrier | |
| YLR349W | 3.5 | DIC1 reverse internal | |||
| YKL217W | JEN1 | 3.5 | 2.8 | + | Monocarboxylic acid transporter |
| YNL202W | SPS19 | 3.4 | 3.2 | + | Peroxisomal 2,4-dienoyl-CoA reductase |
| YGL254W | FZF1 | 3.4 | Transcription factor; sulfite metabolism | ||
| YJL213W | 3.3 | Similar to arylidialkylphosphatase | |||
| YMR303C | ADH2 | 3.1 | Alcohol dehydrogenase II | ||
| YCR010C | 3.0 | 12.2 | + | Similar to YDR384C and YNR002C | |
| YNR060W | FRE4 | 3.0 | Similar to ferric reductase; electron transport | ||
| YGR260W | TNA1 | 3.0 | Nicotinic acid transporter | ||
| YGL062W | PYC1 | 2.9 | Pyruvate carboxylase | ||
| YNL203C | 2.8 | 3.2 | |||
| YLR089C | 2.6 | Mitochondrial alanine aminotransferase | |||
| YPL147W | PXA1 | 2.6 | 6.3 | + | ABC family long-chain fatty acid transporter |
| YBR105C | VID24 | 2.5 | Peripheral vesicle membrane protein | ||
| YJR148W | BAT2 | 2.5 | Branched-chain amino acid transaminase | ||
| YOL147C | PEX11 | 2.4 | 2.8 | + | Peroxisome biogenesis |
| YER187W | 2.3 | ||||
| YLR004C | 2.3 | Similar to allantoate permease | |||
| YNL012W | SPO1 | 2.3 | Similar to phospholipase B | ||
| YPL281C | ERR2 | 2.2 | Similar to enolase | ||
| YDL174C | DLD1 | 2.2 | Mitochondrial D-lactate dehydrogenase | ||
| YOL119C | 2.2 | Potential monocarboxylate transporter | |||
| YPL018W | CTF19 | 2.2 | 3.2 | Kinetochore protein | |
| YAR068W | 2.2 | ||||
| YMR191W | 2.2 | 3.1 | |||
| YNL279W | 2.2 | ||||
| YOL059W | GPD2 | 2.1 | Glycerol-3-phosphate dehydrogenase (NAD+) | ||
| YBR132C | AGP2 | 2.1 | Carnitine transport across plasma membrane |