Table 1. SaeR/S-mediated factors elicit host pro-inflammatory transcription during invasive disease.

Gene symbol	Encoded protein	Fold-regulation change	P value
ifng	Interferon gamma	−11.27	≤0.05
tnfrsf1a	Tumor necrosis factor receptor superfamily, member 1a	−3.03	≤0.01
il18	Interleukin 18	−7.17	≤0.01
cd40lg	CD40 ligand	−4.92	≤0.01
il1b	Interleukin-1β	−4.07	≤0.05
crp	C-reactive protein	−4.43	≤0.05
il11	Interleukin 11	−3.65	≤0.05

NOTE. Genes listed display fold-regulation values of MW2ΔsaeR/S-infected mice relative to MW2-infected mice (3 per group). RNA was collected from all leukocytes isolated from the peritoneum, 4 hours post-infection. Fold-regulation and P values calculated using SA Biosciences™ web-based software utilizing the ΔΔC_t method.