Table 2.
Change in blood pressure (mmHg) by quartiles of cord blood lead exposure based on multivariable regression models: Baltimore THREE Study, 2004–2005 (n = 285).
| Parameter | First quartile | Second quartile | Third quartile | Fourth quartile | p-Trend |
|---|---|---|---|---|---|
| n | 72 | 72 | 71 | 70 | |
| Lead (μg/dL) | ≤ 0.46 | 0.47–0.65 | 0.66–0.95 | ≥ 0.96 | |
| Admission | |||||
| SBP | Referent | 2.89 (−2.16 to 7.94) | 1.05 (−4.04 to 6.14) | 6.87 (1.51 to 12.21)* | 0.033* |
| DBP | Referent | 0.00 (−3.95 to 3.96) | 0.81 (−3.17 to 4.80) | 4.40 (0.21 to 8.59)* | 0.036* |
| Maximum | |||||
| SBP | Referent | 2.47 (−3.08 to 8.02) | −1.76 (−7.36 to 3.85) | 7.72 (1.83 to 13.60)* | 0.055 |
| DBP | Referent | 3.93 (−2.86 to 10.72) | −0.42 (−7.27 to 6.43) | 8.33 (1.14 to 15.53)* | 0.086 |
Multivariable linear regression models were controlled for maternal age, maternal race, neighborhood median household income, primaparity, smoking during pregnancy, prepregnancy BMI, and anemia. p-Trend is based on a quartile model.
*
p < 0.05.