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. Author manuscript; available in PMC: 2013 Jul 1.
Published in final edited form as: Nutr Metab Cardiovasc Dis. 2010 Dec 28;22(7):598–604. doi: 10.1016/j.numecd.2010.10.017

Table 1.

Plasma leptin, insulin and glucose concentrations during HFD and HFD plus daily oral gavage with vehicle or s-EH inhibitor (s-EHi, AR9281) in wild-type mice.

Plasma Leptin
(ng/mL)
Plasma Insulin
(µU/mL)
Plasma Glucose
(mg/dL)

Vehicle (n=8)
HFD – Week 5 36.3 ± 5.5 69.1 ± 9.4 310 ± 12
HFD+TT – Week 10 44.0 ± 9.3 47.8 ± 9.1 242 ± 14#
s-EHi (n=10)
HFD – Week 5 41.9 ± 4.8 56.5 ± 12.6 320 ± 11
HFD +TT – Week 10 33.4 ± 3.9# 42.2 ± 7.7 227 ± 11#

HFD = high fat diet; TT = treatment with vehicle or s-EHi. Data expressed as means ± SEM.

#

p<0.05 compared to HFD – Week 5.