Table 3.
Predictors | Headache days/month | Headache index/month | Medication days/month | Responders | MOH |
---|---|---|---|---|---|
p value | p value | p value | p value | p value | |
Male | 0.019b | 0.035b | 0.051b | 0.14a | 0.18a |
Age | 0.85c (0.03) | 0.65c (0.07) | 0.86c (0.03) | 0.22b | 0.56b |
Years with headache | 0.03c (0.31) | 0.18c (0.19) | 0.04c (0.29) | 0.23b | 0.045b |
Type of intervention (3 groups) | 0.41b | 0.84b | 0.73b | 0.85a | 0.36a |
>2 preventive drugs | 0.63b | 0.71b | 0.19b | 0.52a | 0.42a |
MCS-12 | 0.41c (0.12) | 0.26c (0.16) | 0.67c (0.06) | 0.31b | 0.46b |
PCS-12 | 0.04c (0.29) | 0.027c (0.31) | 0.007c (0.38) | 0.10b | 0.19b |
HADS-anxiety | 0.04c (0.29) | 0.0125c (0.32) | 0.14c (0.21) | 0.004b | 0.15b |
HADS-depression | 0.06c (0.26) | 0.0136c (0.30) | 0.057c (0.27) | 0.012b | 0.22b |
HADS-total | 0.027c (0.31) | 0.013c (0.35) | 0.056c (0.27) | 0.003b | 0.17b |
Type of drug overused | 0.52b | 0.28b | 0.51b | 0.91a | 0.77a |
Headache diagnosisd | 0.02b | 0.006b | 0.12b | 0.027a | 0.82a |
Employed, full-time or part-time | 0.08b | 0.06b | 0.25b | 0.14a | 0.18a |
≤9 years of education | 0.82b | 0.32b | 0.06b | 0.54a | 0.04a |
Surgery during follow-up | 0.42b | 0.18b | 0.26b | 0.83a | 0.59a |
aChi square test
bKruskal–Wallis test
cSpearman’s rho with correlation coefficient in brackets
dThe original headache before they developed MOH at baseline: 18 subjects had pure migraine, 17 tension-type headache without migrainous features, and 15 mixed headache