. Author manuscript; available in PMC: 2011 Oct 1.

Published in final edited form as: Nat Neurosci. 2011 Feb 27;14(4):459–468. doi: 10.1038/nn.2779

Table 1.

The fraction of downregulated, but not upregulated TDP-43 targets increased with intron size

Number of TDP-43 targets among expressed, downregulated, or upregulated genes, grouped by their mean intron length as indicated. The percentages in parentheses represent the fraction of TDP-43 targets found in each group upon TDP-43 depletion.

Mean intron length (kb)	Expressed genes	TDP-43 targets	Downregulated genes	Downregulated TDP-43 targets	Upregulated genes	Upregulated TDP-43 targets
0–1	2566	510 (20%)	31	8 (26%)	100	7 (7%)
1–10	8022	4485 (56%)	80	47 (59%)	252	56 (32%)
10–100	1238	1027 (83%)	109	104 (95%)	10	3 (30%)
>100	26	26 (100%)	19	19 (100%)	0	0 (0%)
Total	11852	6048 (51%)	239	178 (74%)	362	66 (18%)