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. Author manuscript; available in PMC: 2011 May 16.
Published in final edited form as: Ann N Y Acad Sci. 2008;1131:13–36. doi: 10.1196/annals.1413.002

FIGURE 14.

FIGURE 14

NIR optical lymph imaging detects pulsatile flow in humans. (A) White-light and NIR fluorescent image overlay of a subject with breast cancer. Intradermal injection is performed with 100 μL of 20 μg IC-Green in the peri-areolar region on the right breast. Arrow identifies a lymph channel on patient’s left breast. (B) Plot of intensity profile at a ROI (oval in A) as a function of duration of image acquisition. The peaks indicate that lymph channel conducts the bolus of IC-Green from the injection site to axilla on an average every 22.9 ± 7.8 s.