Skip to main content
. Author manuscript; available in PMC: 2011 May 16.
Published in final edited form as: Chembiochem. 2010 Mar 1;11(4):573–580. doi: 10.1002/cbic.200900674

Table 1.

Cell growth inhibition by 2- and 4-trifluoromethylcinnamoyl-SNAc (1c and 1e), their corresponding pyrones (2c and 2e), and 4-methylcinnamoyl pyrone (2g) on human normal (MCF-10A) and tumor-derived cell lines (MCF-7 and BT-474).


Cell line
Compounds

BT-474
IC50m)
MCF-7

MCF-10A
Compound 2e 0.03 ± 0.001 0.3 ± 0.02 > 100
Compound 1e 1.0 ± 0.1 1.5 ± 0.2 > 100
Compound 2c 0.12 ± 0.02 3.1 ± 0.1 > 100
Compound 1c 5.5 ± 0.2 15 ± 0.2 > 100
Compound 2g 55 ± 1.5 > 100 > 100