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Type 1 diabetes incidence of NOD, NOD.CD38-/-, NOD.P2X7-/-, and NOD.CD38-/-.P2X7-/- females. *P<0.005 compared to all other three strains (Kaplan–Meier log-rank analysis). There is no statistical difference between NOD and NOD.P2X7-/- or NOD and NOD.CD38-/-.P2X7-/- mice. #The T1D development rate between NOD.P2X7-/-, and NOD.CD38-/-.P2X7-/- mice is significantly different (P=0.0304, Kaplan–Meier log-rank analysis).
