Table 2. Methylation levels in subtypes of invasive breast carcinoma.

	Methylation level (mean ± SD, median)
Gene	Basal-like (n = 33)	Luminal (n = 57)	HER2 (n = 24)	p value*
TWIST	9.1 ± 20.0, 0.19	30.4 ± 35.5, 11.64	20.7 ± 27.6, 9.37	0.002
RASSF1A	15.0 ± 22.3, 1.59	38.0 ± 27.7, 40.01	23.0 ± 21.4, 13.87	<0.0001
HIN-1	12.8 ± 28.5, 0.01	38.9 ± 43.4, 6.59	37.7 ± 37.5, 32.18	0.004
APC1	18.9 ± 32.2, 0.30	31.9 ± 38.4, 1.25	45.9 ± 35.1, 55.87	0.023
CDH1	1.7 ± 4.4, 0.01	0.5 ± 1.7, 0.00	2.4 ± 3.6, 0.52	0.0002
BRCA1	21.1 ± 35.5, 0.00	0.8 ± 3.9, 0.00	0.9 ± 4.4, 0.00	0.005
RAR-β	10.7 ± 18.1, 4.38	12.2 ± 20.9, 1.49	14.9 ± 16.1, 10.94	0.098
CYCLIN D2	10.5 ± 24.9, 0.00	18.2 ± 30.1, 0.48	13.7 ± 24.0, 0.26	0.223
ESR1	0.2 ± 0.9, 0.00	0.7 ± 2.9, 0.00	2.2 ± 9.5, 0.00	0.641

^*p value obtained using the nonparametric Kruskal-Wallis test.