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. Author manuscript; available in PMC: 2011 May 16.
Published in final edited form as: Lung Cancer. 2010 Jul 31;71(3):271–282. doi: 10.1016/j.lungcan.2010.06.002

Fig. 5.

Fig. 5

Expression of apoptotic proteins in tumors (A) and (B) quantitation of apoptotic protein expression. Whole-cell lysates from control-untreated and treated tumors were analyzed by western blotting for PARP, cleaved PARP, caspase 3, 8 and 9 protein expressions. Lane 1, untreated control tumors; lane 2, oral Nos 300 mg/kg; lane 3, Cis 2.5 mg/kg i.v. (q4d × 3 schedule); lane 4; Cis + Nos. β-Actin protein acts as a loading control. Similar results were observed in replicate experiments. Protein expression levels (relative to β-actin) were determined. Mean ± SE for three replicate determinations. One-way ANOVA followed by post-Tukey test was used for statistical analysis. P < 0.01 (*significantly different from untreated controls; **significantly different from Nos and Cis single treatments; ■ significantly different from Cis single treatment).