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Sequencing of newly synthesized viral cDNAs. (A) Nucleotide sequence alignment of HIV-1 cDNA from cells infected with HIV-1 carrying A3DE, A3DE C320Y, or A3G. The pNL4-3 sequence from nucleotides 5699 to 6076 is shown on the top. Only the mutated nucleotides are shown. Dots indicate nucleotides identical to pNL4-3 sequences. (B) Comparison of dinucleotide consensus sequences for A3DE C320Y and A3G editing. Higher frequencies are in bold. Targeted guanines are underlined.
