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Inhibited Mga2p activation and BMV RNA replication can be restored or partially restored in ubp6Δ and ufd3Δ cells by supplementation with Ub. (A) BMV RNA replication and (B) Mga2p activation were assessed in wt, ufd3Δ, and ubp6Δ cells with or without the addition of Ub. BMV 1a was expressed in all cells in panel B. Accumulation of BMV RNAs and activation of Mga2p were analyzed as in Fig. 1 and 5, respectively.
