Table 4.

Antibody-mediated inhibition of RRV plaque formation on Vero cell monolayers by anti-RRV polyclonal sera or RRV E2 protein-specific monoclonal antibodies^a

Anti-RRV antibody	Highest antibody dilution to achieve 50% RRV plaque inhibition
	RRV-T48	RRVPERS
Polyclonal anti-RRVb	1.5 × 10−5	1.9 × 10−5
MAb E7c	7.5 × 10−5	<10−1
MAb 10C9c	1.2 × 10−4	3.5 × 10−4
MAb 3C4c	1.2 × 10−6	<10−1

^aAll antibodies were titrated by 1/10 serial dilution from 1/50 × 10⁶ to 1/5 × 10⁶ prior to mixing with 200 PFU of purified RRV.

^bPolyclonal antibody to RRV raised in ascitic fluid to PEG-purified RRV-T48.

^cSpecific for the E2 protein of RRV.