Fig. 8.

Impact of hippuristanol on SG formation in HeLa and Vero cells. HeLa cells (A) or Vero cells (B) were mock treated or infected with KOS1.1 and ΔSma at an MOI of 10. Hippuristanol was added at 1 hpi. At 16 hpi, cells were stained for TIA-1 (green), ICP4 (pink), and DNA (DAPI; blue). Images shown represent the largest amount of hippuristanol without formation of SGs, the smallest amount of hippuristanol inducing SGs, and a larger amount of hippuristanol showing dose-dependent increase of SG formation.