Table 2.

Measures of intrahost genetic diversity of Ross River virus from epidemic polyarthritis patients

Straina	Gene/protein	No. of clones sequenced	No. of clones with consensus sequence	Total no. of variable nt sites	Total no. of variable aa sites	Total no. of nt changesb	Total no. of aa changes	Mean pairwise divergence (%)	dN/dS
PW7S (serum)	E2	16	1	48	35	50	37	0.49	1.43
	nsP3	19	3	32	21	37	25	0.23	0.97
PW7I (isolate)	E2	22	12	12	9	13	10	0.09	1.34
	nsP3	23	11	19	11	19	11	0.10	0.61
PW11	E2	19	3	40	28	49	35	0.40	0.97
	nsP3	22	1	55	36	150	49	0.60	0.61
PW14	E2	22	14	10	7	11	8	0.08	1.03
	nsP3	22	5	38	21	40	22	0.21	0.51
SN11c	E2	0	0	0	0	0	0	0	0
	nsP3	22	2	62	27	161	49	0.72	0.30
SN39	E2	21	9	31	14	33	15	0.25	0.40
	nsP3	21	3	49	33	49	33	0.29	0.80
SN85	E2	20	6	53	28	70	39	0.53	0.53
	nsP3	24	0	112	67	143	84	0.70	0.67
Total E2 serum						213
Total nsP3 serum						580

^aRefer to Table 1 for details of patients from whom viruses were derived.

^bValues for nsP3 and for E2 in boldface type are significantly different (P < 0.05, chi-square test).

^cThere was insufficient serum for testing from patient SN11.