Figure 3.
At least one week after the tail cuff measurements, adult mice that received neonatal saline or leptin were placed within an open field (■: control-saline, n=8 male, 10 female;□s: GR-saline, n=14 male, 8 female; ▨: control-leptin, n=12 male, 9 female; ▤: GR-leptin, n=15 male, 6 female). Video tracking software recorded movement throughout the 1648 cm2 of open space (A), including movements exploring the central 645 cm2 (B). Neonatal growth restriction decreased the activity of adult males (A; F(1,45)=7.0, *P<0.05 versus control-saline).