Fig 7. scFv-NKG2D treatment significantly increases T cell infiltration in a B16F10 melanoma model.
Infiltration of CD4+ (A) and CD8+ (C) T cells was analyzed by flow cytometry on excised B16F10 tumor tissues 19 days post-inoculation. Results shown are pooled data from two independent experiments and are demonstrated as fold-increase, in which the average % in the WT B16F10-injected group was designated as 1. *: p<0.01. CD69 expression on CD4+ (B) and CD8+ (D) T cells was also analyzed.