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Time-course of the antinociceptive effect of T. catigua hydroalcoholic extract (200 mg kg−1, p.o) on the hot-plate test in mice. Results are presented as the mean ± SEM; n = 10–12 animals per group. *P < .05 significantly different from PBS-treated group (ANOVA followed by Newmann-Keuls post-hoc test).
