Figure 2.
Effect of prophylactic treatment with T. catigua extract (200 mg kg−1, p.o.) and dexamethasone (1 mg kg−1, i.p.) on the mechanical hypersensitivity induced by carrageenan (300 μg/50 μl/paw, i.pl.) in mice. (a) Time-course of the anti-hypernociceptive effect; (b) AUC of the anti-hypernociceptive effect. Results represent the mean ± SEM; n = 6–8 animals per group. *P < .05 significantly different from PBS + PBS-treated mice; # P < .05 significantly different from PBS + carrageenan-treated mice (ANOVA followed by Newmann-Keuls post-hoc test).