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. Author manuscript; available in PMC: 2011 Aug 1.
Published in final edited form as: Curr Opin Neurobiol. 2010 Sep 9;21(1):182–188. doi: 10.1016/j.conb.2010.08.014

Table 1.

Phenotypic Comparisons between Spastin, Atlastin, and Spichthyin

Null allele Bouton clustering Satellite
boutons
Bouton number Temperature-
sensitivity
Microtubules Escaper
Sterility
Escaper
movement
Atlastin more clustered Yes increased by 17% Yes dense network yes Highly impaired
Spastin more clustered Yes increased by 60% Yes dense network yes Highly impaired
Spichthyin more clustered No* increased by 100% Not tested* dense network fertile Normal*
Overexpression Muscle attachment Acetylated Tubulin Microtubules
Atlastin partial/totally detached significantly less faint and sparse
Spastin partial/totally detached significantly less faint and sparse
Spichthyin Not discussed significantly less faint and sparse
*

Personal communication (Cahir O’Kane, 9 July 2010)