Table 2.

Summary of RFRP and OT7T022 mRNA and peptide localization in rhesus macaques.

Cell type	Macaque RFRP	Macaque OT7T022	Avian GnIH	Avian GnIH-R	Rodent RFRP	Rodent GPR74
Spermatogonia	✓	✓	✓	✓	✓
Spermatocytes	✓	✓	✓	✓	✓
Spermatids	-	-	-	-	✓	✓
Spermatozoa	-	-	-	-	✓	✓
Sertoli cells	-	✓	-	-	-	-
Leydig cells	✓	✓
Seminiferous tubules	✓	✓	✓	✓	✓	✓
Interstitium	✓	✓	✓	✓	-	-
Oocytes	✓	✓	-	-
Granulosa cells	✓	✓	✓	✓
Thecal cells	-	-	✓	✓

Avian GnIH mRNA and peptide and GnIH-R mRNA and binding sites characterized in European starlings (Sturnus vulgaris, Bentley et al., 2008), house sparrows (Passer domesticus, McGuire and Bentley, 2010), Japanese quail (Coturnix japonica, Bentley et al., 2008) and domestic chicken (Gallus gallus, Maddineni et al., 2008). Rodent RFRP and GPR74 peptides characterized in hamster (Mesocricetus auratus, Zhao et al., 2010). Checkmarks indicate presence in the cell type, dashes denote lack of mRNA, peptide or binding sites and blank spaces indicate lack of evidence.